Pneumomediastinum in dermatomyositis itself is not a poor prognostic factor: report of a case and review of the literature
Identifieur interne : 001974 ( Main/Exploration ); précédent : 001973; suivant : 001975Pneumomediastinum in dermatomyositis itself is not a poor prognostic factor: report of a case and review of the literature
Auteurs : Ken Yoshida [Japon] ; Daitaro Kurosaka [Japon] ; Isamu Kingetsu [Japon] ; Kenichiro Hirai [Japon] ; Akio Yamada [Japon]Source :
- Rheumatology International [ 0172-8172 ] ; 2008-07-01.
English descriptors
Abstract
Abstract: We describe a 38-year-old man who presented with proximal muscle weakness, myalgia, polyarthralgia, and skin rash and was diagnosed as having dermatomyositis (DM). The patient’s symptoms improved with prednisolone therapy. However, myopathy relapsed and pneumomediastinum with subcutaneous emphysema developed. Pneumomediastinum with subcutaneous emphysema rapidly disappeared by the administration of ciclosporin. We reviewed the present case and previously reported cases regarding the clinical characteristics. All of the reported death cases were accompanied by interstitial lung disease (ILD). Although it has been reported that pneumomediastinum in DM can be fatal, the direct cause of patient’s death was due to respiratory failure resulting from progressive ILD. Pneumomediastinum without ILD shows a good prognosis.
Url:
DOI: 10.1007/s00296-008-0548-1
Affiliations:
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polyarthralgia, and skin rash and was diagnosed as having dermatomyositis (DM). The patient’s symptoms improved with prednisolone therapy. However, myopathy relapsed and pneumomediastinum with subcutaneous emphysema developed. Pneumomediastinum with subcutaneous emphysema rapidly disappeared by the administration of ciclosporin. We reviewed the present case and previously reported cases regarding the clinical characteristics. All of the reported death cases were accompanied by interstitial lung disease (ILD). Although it has been reported that pneumomediastinum in DM can be fatal, the direct cause of patient’s death was due to respiratory failure resulting from progressive ILD. 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